Dialysis Adequacy and Risk of Dementia in Elderly Hemodialysis Patients.

ABSTRACT: Objective: Dementia is prevalent among elderly patients undergoing hemodialysis. However, the association between dialysis adequacy and the risk of dementia is uncertain. Methods: A total of 10,567 patients aged >65 years undergoing maintenance hemodialysis who participated in a national hemodialysis quality assessment program were analyzed. The patients were classified into quartile groups based on single-pool Kt/V levels. The associations between single-pool Kt/V and the development of dementia, Alzheimer's disease (AD), and vascular dementia (VD) were examined. Results: The mean age of the patients was 72.9 years, and 43.4% were female. The mean baseline single-pool Kt/V level was 1.6 ± 0.3. During a median follow-up of 45.6 (45.6-69.9) months, there were 27.6, 23.9, and 2.8 events/1,00

SUBMITTER: Kim HW 

PROVIDER: S-EPMC8669136 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature