Metabolic changes during periodontitis therapy assessed by real-time ambient mass spectrometry.

ABSTRACT: It has been shown that bacteria in periodontally diseased patients can be recognized by the detection of volatile metabolites in the headspace of saliva by real-time ambient mass spectrometry. The aim of this study was to use this detection method to analyze the oral metabolome in diseased periodontitis patients before and after therapy to monitor disease evolution and healing events. Twelve patients with advanced chronic periodontal disease and 12 periodontally healthy controls served as test and control groups, respectively. Clinical data, subgingival plaque samples and saliva samples were collected at baseline (BL) and 3 months after treatment. The test group received non-surgical scaling and root planing using systemic antibiotics and the control group received one session of supraging

SUBMITTER: Bregy L 

PROVIDER: S-EPMC8669448 | biostudies-literature | 2019 Sep

REPOSITORIES: biostudies-literature