Effect of electro-acupuncture on ovarian function of women with diminished ovarian reserve: study protocol for a randomized controlled trial.

ABSTRACT: BACKGROUND:Diminished ovarian reserve (DOR) is the precursor state of ovarian failure and can cause the decline of women's reproductive function. DOR also leads to poor outcome of in vitro fertilization and embryo transfer (IVF-ET) by affecting the oocytes, high qualified embryo rate, pregnancy rate, etc. Some studies have demonstrated that acupuncture can improve ovarian function. But to date, there is limited evidence indicating that acupuncture or electro-acupuncture is efficient to DOR. This trial aims to evaluate the efficiency and safety of electro-acupuncture for the ovarian function and the following outcome of IVF-ET in DOR patients. METHODS:This will be a multicenter randomized controlled clinical trial. A total of more than 338 women with DOR will be randomly allocated to treatm

SUBMITTER: Yang L 

PROVIDER: S-EPMC8670117 | biostudies-literature | 2021 Dec

REPOSITORIES: biostudies-literature