Deep brain stimulation in the subthalamic nuclei alters postural alignment and adaptation in Parkinson's disease.

ABSTRACT: Parkinson's disease (PD) can produce postural abnormalities of the standing body position such as kyphosis. We investigated the effects of PD, deep brain stimulation (DBS) in the subthalamic nucleus (STN), vision and adaptation on body position in a well-defined group of patients with PD in quiet standing and during balance perturbations. Ten patients with PD and 25 young and 17 old control participants were recruited. Body position was measured with 3D motion tracking of the ankle, knee, hip, shoulder and head. By taking the ankle as reference, we mapped the position of the joints during quiet standing and balance perturbations through repeated calf muscle vibration. We did this to explore the effect of PD, DBS in the STN, and vision on the motor learning process of adaptation in response

SUBMITTER: Fransson PA 

PROVIDER: S-EPMC8670690 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature