Prevalence and clinical course of upper airway respiratory virus infection in critically ill patients with hematologic malignancies.

ABSTRACT:

Background

The clinical significance of upper airway respiratory virus (RV) detection in patients with hematologic malignancies remains unclear. We aimed to investigate the association between upper airway RV detection and prognosis in critically ill patients with hematologic malignancies.

Methods

This retrospective observational study included 331 critically ill patients with hematologic malignancies who presented respiratory symptoms and their nasopharyngeal swab was tested using a multiplex PCR assay between January 2017 and December 2018. A logistic regression model was used to adjust for potential confounding factors in the association between assay positivity and in-hospital mortality.

Results

Among the 331 analyzed patients, RVs were detected in 29.0%. The over

SUBMITTER: Lee J 

PROVIDER: S-EPMC8670702 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature