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ABSTRACT: Aim
To clarify the extent to which medical comorbidities and goals-of-care decisions influence death among individuals with childhood-onset hydrocephalus.Method
This was a retrospective cohort study of 1705 individuals (759 males, 946 females, mean age 11y 5mo, SD 6y 6mo, range 0-37y 7mo at last follow-up) with childhood-onset hydrocephalus, of whom 88 (5.2%) were deceased. Existing medical records, death records, and publicly available internet sources were analyzed. We estimated hazard ratios for putative risk factors through Cox regression based upon 10 529 person-years of data and quantitatively and qualitatively analyzed the circumstances surrounding each death.Results
Mortality did not differ statistically by demographic factors, although higher proportions of
SUBMITTER: Tully HM
PROVIDER: S-EPMC8671148 | biostudies-literature | 2022 Jan
REPOSITORIES: biostudies-literature