Indoor Environmental Factors May Modify the Response to Mouse Allergen Reduction Among Mouse-Sensitized and Exposed Children with Persistent Asthma.

ABSTRACT:

Background

Whether concomitant home exposures modify the effectiveness of mouse allergen reduction among mouse-sensitized children with asthma is unknown.

Objective

To determine whether a lower baseline home mouse allergen level, lower particulate matter 10 μ or less (PM₁₀), and the absence of sensitization and exposure to other indoor allergens are associated with greater improvements in asthma associated with mouse allergen reduction.

Methods

A secondary analysis of a randomized clinical trial of a home mouse allergen intervention was performed to examine the effect of 3 indoor factors on the relationship between mouse allergen reduction and a range of asthma outcomes.

Results

Participants (N = 297) were predominantly minority (78% African American

SUBMITTER: Sadreameli SC 

PROVIDER: S-EPMC8671238 | biostudies-literature | 2021 Dec

REPOSITORIES: biostudies-literature