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Bisoprolol and/or hyperoxic breathing do not reduce hyperventilation in pulmonary arterial hypertension patients.

ABSTRACT: Hyperventilation is common in pulmonary arterial hypertension and may be related to autonomic imbalance. Patients underwent exercise testing and hyperoxic breathing before and after bisoprolol treatment. We found that neither beta blocker treatment nor hyperoxic breathing in patients reduced hyperventilation at rest and during exercise, although it reduced heart rate.

SUBMITTER: Peters EL

PROVIDER: S-EPMC8671678 | biostudies-literature | 2021 Oct-Dec

REPOSITORIES: biostudies-literature

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Bisoprolol and/or hyperoxic breathing do not reduce hyperventilation in pulmonary arterial hypertension patients.

Peters Eva L EL van Campen Jasmijn S J A JSJA Groepenhoff Herman H de Man Frances S FS Vonk Noordegraaf Anton A Bogaard Harm J HJ

Pulmonary circulation 20211001 4

Hyperventilation is common in pulmonary arterial hypertension and may be related to autonomic imbalance. Patients underwent exercise testing and hyperoxic breathing before and after bisoprolol treatment. We found that neither beta blocker treatment nor hyperoxic breathing in patients reduced hyperventilation at rest and during exercise, although it reduced heart rate. ...[more]

PMID: 34925761

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