Association Between Preserved Ratio Impaired Spirometry and Clinical Outcomes in US Adults.

ABSTRACT:

Importance

Chronic lung diseases are a leading cause of morbidity and mortality. Unlike chronic obstructive pulmonary disease, clinical outcomes associated with proportional reductions in expiratory lung volumes without obstruction, otherwise known as preserved ratio impaired spirometry (PRISm), are poorly understood.

Objective

To examine the prevalence, correlates, and clinical outcomes associated with PRISm in US adults.

Design, setting, and participants

The National Heart, Lung, and Blood Institute (NHLBI) Pooled Cohorts Study was a retrospective study with harmonized pooled data from 9 US general population-based cohorts (enrollment, 65 251 participants aged 18 to 102 years of whom 53 701 participants had valid baseline lung function) conducted from 1971-2011 (fin

SUBMITTER: Wan ES 

PROVIDER: S-EPMC8672237 | biostudies-literature | 2021 Dec

REPOSITORIES: biostudies-literature