Enamel Renal Syndrome: Protocol for a Scoping Review.

ABSTRACT:

Background

Enamel renal syndrome (ERS) (OMIM 204690) is a rare autosomal recessive disorder characterized by hypoplastic amelogenesis imperfecta, failed tooth eruption, intrapulpal calcifications, gingival enlargement, and nephrocalcinosis. The rarity of the condition and the variability of the phenotype has led to ERS not being fully characterized.

Objective

This scoping review aims to account for the range and current state of knowledge on ERS and synthesize these findings into a comprehensive summary, focusing on the pathophysiology, genotype-phenotype correlations, and patient management from a dental perspective.

Methods

The authors will conduct a systematic search of PubMed (MEDLINE), BioMed Central, EbscoHost Web, Web of Science, and WorldCat. We will include a

SUBMITTER: Roomaney IA 

PROVIDER: S-EPMC8672286 | biostudies-literature | 2021 Nov

REPOSITORIES: biostudies-literature