Wearable biosensors have the potential to monitor physiological changes associated with opioid overdose among people who use drugs: A proof-of-concept study in a real-world setting.

ABSTRACT:

Introduction

Wearable biosensors have the potential to monitor physiological change associated with opioid overdose among people who use drugs.

Methods

We enrolled 16 individuals who reported ≥ 4 daily opioid use events within the previous 30 day. Each was assigned a wearable biosensor that measured respiratory rate (RR) and actigraphy every 15 s for 5 days and also completed a daily interview assessing drug use. We describe the volume of RR data collected, how it varied by participant characteristics and drug use over time using repeated measures one-way ANOVA, episodes of acute respiratory depression (≤5 breaths/minute), and self-reported overdose experiences.

Results

We captured 1626.4 h of RR data, an average of 21.7 daily hours/participant over follow-up. Individ

SUBMITTER: Roth AM 

PROVIDER: S-EPMC8672322 | biostudies-literature | 2021 Dec

REPOSITORIES: biostudies-literature