Changes in the use of diabetes drugs among community-dwelling people with Alzheimer's disease.

ABSTRACT:

Background

Type 2 diabetes is common in persons with Alzheimer's disease (AD). Management of diabetes in persons with AD is challenging due to changing goals of care and susceptibility to adverse drug events including hypoglycemia. The aim of this study was to investigate the prevalence of diabetes drug use from 5 years before to 5 years after the time of AD diagnosis among persons with and without AD.

Methods

This was a nationwide register-based study of persons with and without AD and diabetes in Finland. We analyzed data from the Medication Use and Alzheimer's disease (MEDALZ) study that included 70,718 community-dwelling people diagnosed with AD from 2005 to 2011. The study population included 8418 persons with AD and 6666 matched persons without AD who were diagnosed wi

SUBMITTER: Lopez-Rubio C 

PROVIDER: S-EPMC8672592 | biostudies-literature | 2021 Dec

REPOSITORIES: biostudies-literature