Cellular and Extracellular Vesicle RNA Analysis in the Global Threat Fungus Candida auris.

ABSTRACT: Emerging and reemerging pathogens are a worldwide concern, and it is predicted that these microbes will cause severe outbreaks. Candida auris affects people with weakened immune systems, particularly those who are hospitalized or are in health care facilities. Extracellular vesicles (EVs) are lipid bilayer structures released by organisms from all domains of life. EVs can deliver functional molecules to target cells, including proteins and nucleic acids, especially RNA molecules. EVs from several pathogenic fungi species play diverse biological roles related to cell-cell communication and pathogen-host interaction. In this study, we describe a data set which we produced by sequencing the RNA content of EVs from C. auris under normal growth conditions and in the presence of the antifungal c

SUBMITTER: Munhoz da Rocha IF 

PROVIDER: S-EPMC8672890 | biostudies-literature | 2021 Dec

REPOSITORIES: biostudies-literature