Dementia and autopsy-verified causes of death in racially-diverse older Brazilians.

ABSTRACT:

Background

While dementia has been associated with specific causes of death, previous studies were relatively small autopsy series or population-based studies lacking autopsy confirmation and were restricted to Non-Latinx Whites. Here, we examine the association of dementia with autopsy-verified causes of death in racially-diverse older Brazilians.

Methods

As part of the Pathology, Alzheimer´s and Related Dementias Study (PARDoS), a community-based study in Brazil, we included 1941 racially-diverse deceased, 65 years or older at death. We conducted a structured interview with legal informants including the Clinical Dementia Rating (CDR) Scale for dementia proximate to death. Causes of death were assessed after full-body autopsy and macroscopic examination of the brain, thora

SUBMITTER: Farfel JM 

PROVIDER: S-EPMC8673625 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature