Customizing MRI-Compatible Multifunctional Neural Interfaces through Fiber Drawing.

ABSTRACT: Fiber drawing enables scalable fabrication of multifunctional flexible fibers that integrate electrical, optical and microfluidic modalities to record and modulate neural activity. Constraints on thermomechanical properties of materials, however, have prevented integrated drawing of metal electrodes with low-loss polymer waveguides for concurrent electrical recording and optical neuromodulation. Here we introduce two fabrication approaches: (1) an iterative thermal drawing with a soft, low melting temperature (Tm) metal indium, and (2) a metal convergence drawing with traditionally non-drawable high Tm metal tungsten. Both approaches deliver multifunctional flexible neural interfaces with low-impedance metallic electrodes and low-loss waveguides, capable of recording optically-evoked and s

SUBMITTER: Antonini MJ 

PROVIDER: S-EPMC8673858 | biostudies-literature | 2021 Oct

REPOSITORIES: biostudies-literature