Clinical Outcomes of Patients With Primary Membranous Nephropathy and Subnephrotic Proteinuria.

ABSTRACT: Objectives: To update the information about the prognosis of patients with primary membranous nephropathy (MN) and subnephrotic proteinuria and identify the relevant predictors. Methods: In total, 474 cases of biopsy-proven primary MN with at least 18 months of follow-up were reviewed to determine the outcomes of the subgroup of patients that presented with subnephrotic proteinuria. Clinical data included initial proteinuria and microhematuria, defined as the average proteinuria/microhematuria of the first 6 months during the course. Outcomes included partial remission (PR), complete remission (CR), nephrotic proteinuria progression, and kidney function progression, defined as ≥50% loss of kidney function or end-stage kidney disease. Results: In total, 205 patients wit

SUBMITTER: He P 

PROVIDER: S-EPMC8674415 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature