Postoperative Adjuvant Radiotherapy in Atypical Meningioma Patients: A Meta-Analysis Study.

ABSTRACT:

Background and purpose

Consensus regarding the need for adjuvant radiotherapy (RT) in patients with atypical meningiomas (AMs) is lacking. We compared the effects of adjuvant RT after surgery, gross total resection (GTR), and subtotal resection (STR) on progression-free survival (PFS) and overall survival (OS) in patients with AMs, respectively.

Methods

We performed a systematic review and meta-analysis of the literature published in PubMed, Embase, and the Cochrane Library from inception to February 1, 2021, to identify articles comparing the PFS and OS of patients receiving postoperative RT after surgery, GTR and STR.

Results

We identified 2307 unique studies; 24 articles including 3078 patients met the inclusion criteria. The sensitivity analysis results showed tha

SUBMITTER: Song D 

PROVIDER: S-EPMC8674463 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature