Long-lasting effects of chronic exposure to chemical pollution on the hologenome of the Manila clam.

ABSTRACT: Chronic exposure to pollutants affects natural populations, creating specific molecular and biochemical signatures. In the present study, we tested the hypothesis that chronic exposure to pollutants might have substantial effects on the Manila clam hologenome long after removal from contaminated sites. To reach this goal, a highly integrative approach was implemented, combining transcriptome, genetic and microbiota analyses with the evaluation of biochemical and histological profiles of the edible Manila clam Ruditapes philippinarum, as it was transplanted for 6 months from the polluted area of Porto Marghera (PM) to the clean area of Chioggia (Venice lagoon, Italy). One month post-transplantation, PM clams showed several modifications to its resident microbiota, including an overre

SUBMITTER: Iannello M 

PROVIDER: S-EPMC8674894 | biostudies-literature | 2021 Dec

REPOSITORIES: biostudies-literature