Systematic Review: Sweet Syndrome Associated with Inflammatory Bowel Disease.

ABSTRACT:

Background and aims

Sweet syndrome [SS] is a dermatological condition associated with both inflammatory bowel disease [IBD] and azathioprine use. We performed a systematic review to better delineate clinical characteristics and outcomes of SS in IBD patients.

Methods

Peer-reviewed, full-text journal publications from inception to April 2020 in English language and adult subjects with IBD were included. Skin biopsy was required as SS gold-standard diagnosis. Azathioprine-associated SS required recent azathioprine introduction or recurrence of SS after azathioprine re-challenge.

Results

We included 89 publications with 95 patients [mean age of SS diagnosis: 44 years; 59% female; 20 with azathioprine-associated SS and 75 without]. SS was diagnosed prior to IBD in 5.3%, a

SUBMITTER: Sleiman J 

PROVIDER: S-EPMC8675328 | biostudies-literature | 2021 Nov

REPOSITORIES: biostudies-literature