Reproducibility in the absence of selective reporting: An illustration from large-scale brain asymmetry research.

ABSTRACT: The problem of poor reproducibility of scientific findings has received much attention over recent years, in a variety of fields including psychology and neuroscience. The problem has been partly attributed to publication bias and unwanted practices such as p-hacking. Low statistical power in individual studies is also understood to be an important factor. In a recent multisite collaborative study, we mapped brain anatomical left-right asymmetries for regional measures of surface area and cortical thickness, in 99 MRI datasets from around the world, for a total of over 17,000 participants. In the present study, we revisited these hemispheric effects from the perspective of reproducibility. Within each dataset, we considered that an effect had been reproduced when it matched the meta-analyt

SUBMITTER: Kong XZ 

PROVIDER: S-EPMC8675427 | biostudies-literature | 2022 Jan

REPOSITORIES: biostudies-literature