QTL mapping of a Brazilian bioethanol strain links the cell wall protein-encoding gene GAS1 to low pH tolerance in S. cerevisiae.

ABSTRACT:

Background

Saccharomyces cerevisiae is largely applied in many biotechnological processes, from traditional food and beverage industries to modern biofuel and biochemicals factories. During the fermentation process, yeast cells are usually challenged in different harsh conditions, which often impact productivity. Regarding bioethanol production, cell exposure to acidic environments is related to productivity loss on both first- and second-generation ethanol. In this scenario, indigenous strains traditionally used in fermentation stand out as a source of complex genetic architecture, mainly due to their highly robust background-including low pH tolerance.

Results

In this work, we pioneer the use of QTL mapping to uncover the genetic basis that confers to the industrial strain

SUBMITTER: Coradini ALV 

PROVIDER: S-EPMC8675505 | biostudies-literature | 2021 Dec

REPOSITORIES: biostudies-literature