Ventilation practices in burn patients-an international prospective observational cohort study.

ABSTRACT:

Background

It is unknown whether lung-protective ventilation is applied in burn patients and whether they benefit from it. This study aimed to determine ventilation practices in burn intensive care units (ICUs) and investigate the association between lung-protective ventilation and the number of ventilator-free days and alive at day 28 (VFD-28).

Methods

This is an international prospective observational cohort study including adult burn patients requiring mechanical ventilation. Low tidal volume (V _T) was defined as V _T ≤ 8 mL/kg predicted body weight (PBW). Levels of positive end-expiratory pressure (PEEP) and maximum airway pressures were collected. The association between V _T and VFD-28 was analyzed using a competing r

SUBMITTER: Schultz MJ 

PROVIDER: S-EPMC8676707 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature