An Evaluation of Antimicrobial Prescribing and Risk-adjusted Mortality.

ABSTRACT: The Centers for Disease Control and Prevention recommends tracking risk-adjusted antimicrobial prescribing. Prior studies have used prescribing variation to drive quality improvement initiatives without adjusting for severity of illness. The present study aimed to determine the relationship between antimicrobial prescribing and risk-adjusted ICU mortality in the Pediatric Health Information Systems (PHIS) database, assessed by IBM-Watson risk of mortality. A nested analysis sought to assess an alternative risk model incorporating laboratory data from federated electronic health records.

Methods

Retrospective cohort study of pediatric ICU patients in PHIS between 1/1/2010 and 12/31/2019, excluding patients admitted to a neonatal ICU, and a nested study of PHIS+ from 1/1/2010 to 12/31

SUBMITTER: Pelletier JH 

PROVIDER: S-EPMC8678007 | biostudies-literature | 2021 Nov-Dec

REPOSITORIES: biostudies-literature