Neuropathic pain in the IMI-APPROACH knee osteoarthritis cohort: prevalence and phenotyping.

ABSTRACT:

Objectives

Osteoarthritis (OA) patients with a neuropathic pain (NP) component may represent a specific phenotype. This study compares joint damage, pain and functional disability between knee OA patients with a likely NP component, and those without a likely NP component.

Methods

Baseline data from the Innovative Medicines Initiative Applied Public-Private Research enabling OsteoArthritis Clinical Headway knee OA cohort study were used. Patients with a painDETECT score ≥19 (with likely NP component, n=24) were matched on a 1:2 ratio to patients with a painDETECT score ≤12 (without likely NP component), and similar knee and general pain (Knee Injury and Osteoarthritis Outcome Score pain and Short Form 36 pain). Pain, physical function and radiographic joint damage of multipl

SUBMITTER: van Helvoort EM 

PROVIDER: S-EPMC8679113 | biostudies-literature | 2021 Dec

REPOSITORIES: biostudies-literature