Association between bacterial vaginosis and fecundability in Kenyan women planning pregnancies: a prospective preconception cohort study.

ABSTRACT:

Study question

Is bacterial vaginosis (BV) associated with fecundability?

Summary answer

Women with BV may be at increased risk for sub-fecundity.

What is known already

While BV has been associated with poor IVF outcomes, the association between vaginal microbiota disruption and non-medically assisted conception has not been thoroughly explored.

Study design, size, duration

Kenyan women with fertility intent were enrolled in prospective cohort that included monthly preconception visits with vaginal fluid specimen collection and pregnancy testing. Four hundred fifty-eight women attempting pregnancy for ≤3 menstrual cycles at enrollment were eligible for this fecundability analysis.

Participants/materials, setting, methods

At monthly preconception visits,

SUBMITTER: Lokken EM 

PROVIDER: S-EPMC8679172 | biostudies-literature | 2021 Apr

REPOSITORIES: biostudies-literature