Association between preconception paternal health and pregnancy loss in the USA: an analysis of US claims data.

ABSTRACT:

Study question

Is preconception paternal health associated with pregnancy loss?

Summary answer

Poor preconception paternal health is associated with a higher risk of pregnancy loss as confirmed in sensitivity analyses accounting for maternal age and health.

What is known already

Preconception paternal health can negatively impact perinatal outcomes.

Study design, size, duration

Retrospective cohort study of US insurance claims database from 2009 to 2016 covering 958 804 pregnancies.

Participants/materials, setting, methods

US insurance claims database including women, men and pregnancies within the USA between 2007 and 2016. Paternal preconception health status (e.g. metabolic syndrome diagnoses (MetS), Charlson comorbidity index (CCI) and individual chr

SUBMITTER: Kasman AM 

PROVIDER: S-EPMC8679308 | biostudies-literature | 2021 Feb

REPOSITORIES: biostudies-literature