Catecholamines are key modulators of ventricular repolarization patterns in the ball python (Python regius).

ABSTRACT: Ectothermic vertebrates experience daily changes in body temperature, and anecdotal observations suggest these changes affect ventricular repolarization such that the T-wave in the ECG changes polarity. Mammals, in contrast, can maintain stable body temperatures, and their ventricular repolarization is strongly modulated by changes in heart rate and by sympathetic nervous system activity. The aim of this study was to assess the role of body temperature, heart rate, and circulating catecholamines on local repolarization gradients in the ectothermic ball python (Python regius). We recorded body-surface electrocardiograms and performed open-chest high-resolution epicardial mapping while increasing body temperature in five pythons, in all of which there was a change in T-wave polarity. However

SUBMITTER: Boukens BJD 

PROVIDER: S-EPMC8679508 | biostudies-literature | 2022 Feb

REPOSITORIES: biostudies-literature