Outdoor air pollution and anti-Mullerian hormone concentrations in the Sister Study.

ABSTRACT:

Background

Anti-Müllerian hormone (AMH) concentrations are a marker of ovarian reserve and are indicative of a woman's reproductive lifespan. Exposure to tobacco smoke has been associated with lower AMH concentrations; however, less is known about the association between ambient air pollution and ovarian reserve.

Methods

For 883 premenopausal Sister Study participants recruited between 2003 and 2009 in the United States, adult residential annual average concentrations of PM_2.5, PM₁₀, and NO₂ were estimated using validated universal kriging models incorporating land-use regression. We estimated the distance in meters to the nearest major road for both adult enrollment and childhood residences. Serum AMH was measured using an ultrasensitive ELI

SUBMITTER: Gregoire AM 

PROVIDER: S-EPMC8683141 | biostudies-literature | 2021 Oct

REPOSITORIES: biostudies-literature