Ambient air pollution and inflammatory effects in a Canadian pregnancy cohort.

ABSTRACT:

Background

Epidemiologic studies have consistently reported associations between air pollution and pregnancy outcomes including preeclampsia and gestational diabetes. However, the biologic mechanisms underlying these relationships remain unclear as few studies have collected relevant biomarker data. We examined relationships between ambient PM_2.5 and NO₂ with markers of inflammation during pregnancy in a prospective cohort of Canadian women.

Methods

We analyzed data from 1170 women enrolled in the Maternal-Infant Research on Environmental Chemicals study. Daily residential PM_2.5 and NO₂ exposures during pregnancy were estimated using satellite-based and land-use regression models and used to create 14-day and 30-day exposure window

SUBMITTER: Gogna P 

PROVIDER: S-EPMC8683146 | biostudies-literature | 2021 Oct

REPOSITORIES: biostudies-literature