Use of intravenous lipid emulsion therapy as a novel treatment for brevetoxicosis in sea turtles.

ABSTRACT: The southwest coast of Florida experiences annual red tides, a type of harmful algal bloom that results from high concentrations of Karenia brevis. These dinoflagellates release lipophilic neurotoxins, known as brevetoxins, that bind to sodium channels and inhibit their inactivation, resulting in a variety of symptoms that can lead to mass sea turtle strandings. Traditional therapies for brevetoxicosis include standard and supportive care (SSC) and/or dehydration therapy; however, these treatments are slow-acting and often ineffective. Because red tide events occur annually in Florida, our objective was to test intravenous lipid emulsion (ILE) as a rapid treatment for brevetoxicosis in sea turtles and examine potential impacts on toxin clearance rates, symptom reduction, rehabilitation tim

SUBMITTER: Perrault JR 

PROVIDER: S-EPMC8683444 | biostudies-literature | 2021 Dec

REPOSITORIES: biostudies-literature