Salivary cystatin S levels in children with early childhood caries in comparison with caries-free children; statistical analysis and machine learning.

ABSTRACT:

Background

Early childhood caries is the most common infectious disease in childhood, with a high prevalence in developing countries. The assessment of the variables that influence early childhood caries as well as its pathophysiology leads to improved control of this disease. Cystatin S, as one of the salivary proteins, has an essential role in pellicle formation, tooth re-mineralization, and protection. The present study aims to assess salivary cystatin S levels and demographic data in early childhood caries in comparison with caries-free ones using statistical analysis and machine learning methods.

Methods

A cross-sectional, case-control study was undertaken on 20 cases of early childhood caries and 20 caries-free children as a control. Unstimulated whole saliva samples w

SUBMITTER: Koopaie M 

PROVIDER: S-EPMC8683819 | biostudies-literature | 2021 Dec

REPOSITORIES: biostudies-literature