Del Nido versus HTK cardioplegia for myocardial protection during adult complex valve surgery: a retrospective study.

ABSTRACT:

Background

Histidine-tryptophan-ketoglutarate (HTK) and del Nido (DN) cardioplegia are intracellular-type and extracellular-type solution respectively, both can provide a long period of myocardial protection with single-dose infusion, but studies comparing the two are rare for adult cardiac surgery. This study aims to evaluate whether DN is suitable for cardioplegia in complex and high-risk valve surgery with long-term cardiac ischemia when compared with HTK.

Methods

The perioperative records of adult patients infused with DN/HTK as a cardioplegic solution who underwent complex valve surgery with an expected myocardial ischaemic duration longer than 90 min between Oct 2018 and Oct 2019 were analysed retrospectively.

Results

Of the 160 patients who received DN/HTK and

SUBMITTER: Duan L 

PROVIDER: S-EPMC8683821 | biostudies-literature | 2021 Dec

REPOSITORIES: biostudies-literature