Alleviating the effect of quinoa and the underlying mechanism on hepatic steatosis in high-fat diet-fed rats.

ABSTRACT:

Background

Nonalcoholic fatty liver disease (NAFLD) is considered the hepatic component of metabolic syndrome and has attracted widespread attention due to its increased prevalence. Daily dietary management is an effective strategy for the prevention of NAFLD. Quinoa, a nutritious pseudocereal, is abundant in antioxidative bioactive phytochemicals. In the present study, the effects of different amounts of quinoa on the progression of NAFLD and the related molecular mechanism were investigated.

Methods

Male SD rats were simultaneously administered a high fat diet (HF) and different amounts of quinoa (equivalent to 100 g/day and 300 g/day of human intake, respectively). After 12 weeks of the intervention, hepatic TG (triglyceride) and TC (total cholesterol) as well as serum an

SUBMITTER: Song C 

PROVIDER: S-EPMC8684231 | biostudies-literature | 2021 Dec

REPOSITORIES: biostudies-literature