Protein acetylation regulates xylose metabolism during adaptation of Saccharomyces cerevisiae.

ABSTRACT:

Background

As the second most abundant polysaccharide in nature, hemicellulose can be degraded to xylose as the feedstock for bioconversion to fuels and chemicals. To enhance xylose conversion, the engineered Saccharomyces cerevisiae with xylose metabolic pathway is usually adapted with xylose as the carbon source in the laboratory. However, the mechanism under the adaptation phenomena of the engineered strain is still unclear.

Results

In this study, xylose-utilizing S. cerevisiae was constructed and used for the adaptation study. It was found that xylose consumption rate increased 1.24-fold in the second incubation of the yYST12 strain in synthetic complete-xylose medium compared with the first incubation. The study figured out that it was observed at the single-cell level

SUBMITTER: Tan YS 

PROVIDER: S-EPMC8684234 | biostudies-literature | 2021 Dec

REPOSITORIES: biostudies-literature