Targeted cognitive game training enhances cognitive performance in multiple sclerosis patients treated with interferon beta 1-a.

ABSTRACT:

Background

Prevention of cognitive decline in Multiple Sclerosis (MS) is of major importance. We explored the effect of a 6 months computerized game training program on cognitive performance in MS patients with mild cognitive impairment.

Methods

This was a single-center, randomized prospective study. We enrolled in this study 100 eligible MS patients treated with Interferon-beta-1a (Rebif). All had mild cognitive impairment in either executive function or information processing speed. Patients were randomized 1:1 to either use the cognitive games platform by HappyNeuron (HN) or receive no intervention. Executive function and information processing speed scores were measured at 3 and 6 months from baseline to evaluate the effect of game training on cognitive scores.

Result

SUBMITTER: Menascu S 

PROVIDER: S-EPMC8684659 | biostudies-literature | 2021 Dec

REPOSITORIES: biostudies-literature