NR4A1 suppresses pyroptosis by transcriptionally inhibiting NLRP3 and IL-1β and co-localizing with NLRP3 in trans-Golgi to alleviate pathogenic bacteria-induced colitis.
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ABSTRACT:
SUBMITTER: Deng Z
PROVIDER: S-EPMC8684771 | biostudies-literature | 2021 Dec
REPOSITORIES: biostudies-literature
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NR4A1 suppresses pyroptosis by transcriptionally inhibiting NLRP3 and IL-1β and co-localizing with NLRP3 in trans-Golgi to alleviate pathogenic bacteria-induced colitis.
Deng Zhao Z Yang Zhipeng Z Cui Chenbin C Wei Hongkui H Wang Lijia L Tian Dean D Xiao Fang F Peng Jian J
Clinical and translational medicine 20211201 12
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