Sperm quality and absence of SARS-CoV-2 RNA in semen after COVID-19 infection: a prospective, observational study and validation of the SpermCOVID test.

ABSTRACT:

Objective

To study the contagiousness of sperm and its influence on fertility after recovery from COVID-19 infection.

Design

Prospective cohort study.

Setting

University medical center.

Patient(s)

One hundred twenty Belgian men who had recovered from proven COVID-19 infection.

Intervention(s)

No intervention was performed.

Main outcome measure(s)

Semen quality was assessed using the World Health Organisation criteria. DNA damage to sperm cells was assessed by quantifying the DNA fragmentation index and the high density stainability. Finally antibodies against SARS-CoV2 spike-1 antigen, nuclear and S1-receptor binding domain were measured by Elisa and chemilumenscent microparticle immunoassays, respectively.

Result(s)

SARS-CoV-2 RNA was not

SUBMITTER: Donders GGG 

PROVIDER: S-EPMC8685303 | biostudies-literature | 2022 Feb

REPOSITORIES: biostudies-literature