When and why to start continuous renal replacement therapy in critically ill patients with acute kidney injury.

ABSTRACT: Acute kidney injury (AKI) is a common condition in critically ill patients, and may contribute to significant medical, social, and economic consequences, including death. Although there have been advances in medical technology, including continuous renal replacement therapy (CRRT), the mortality rate of AKI is high, and there is no fundamental treatment that can reverse disease progression. The decision to implement CRRT is often subjective and based primarily on the clinician's judgment without consistent and concrete guidelines or protocols regarding when to initiate and discontinue CRRT and how to manage complications. Recently, several randomized controlled trials addressing the initiation of renal replacement therapy in critically ill patients with AKI have been completed, but clinica

SUBMITTER: An JN 

PROVIDER: S-EPMC8685358 | biostudies-literature | 2021 Dec

REPOSITORIES: biostudies-literature