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Disposable Polymeric Nanostructured Plasmonic Biosensors for Cell Culture Adhesion Monitoring.


ABSTRACT: Over the last years, optical biosensors based on plasmonic nanomaterials have gained great scientific interest due to their unquestionable advantages compared to other biosensing technologies. They can achieve sensitive, direct, and label-free analysis with exceptional potential for multiplexing and miniaturization. Recently, it has been demonstrated the potential of using optical discs as high throughput nanotemplates for the development of plasmonic biosensors in a cost-effective way. This work is a pilot study focused on the development of an integrated plasmonic biosensor for the monitoring of cell adhesion and growth of human retinal pigmented cell line (ARPE-19) under different media conditions (0 and 2% of FBS). We observed an increase of the plasmonic band displacement under 2% FBS

SUBMITTER: Vila JC 

PROVIDER: S-EPMC8685410 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature