Comparison of two devices for automated oxygen control in preterm infants: a randomised crossover trial.

ABSTRACT:

Objective

To compare the effect of two different automated oxygen control devices on target range (TR) time and occurrence of hypoxaemic and hyperoxaemic episodes.

Design

Randomised cross-over study.

Setting

Tertiary level neonatal unit in the Netherlands.

Patients

Preterm infants (n=15) born between 24+0 and 29+6 days of gestation, receiving invasive or non-invasive respiratory support with oxygen saturation (SpO₂) TR of 91%-95%. Median gestational age 26 weeks and 4 days (IQR 25 weeks 3 days-27 weeks 6 days) and postnatal age 19 (IQR 17-24) days.

Interventions

Inspired oxygen concentration was titrated by the OxyGenie controller (SLE6000 ventilator) and the CLiO₂ controller (AVEA ventilator) for 24 hours each, in a random sequence

SUBMITTER: Salverda HH 

PROVIDER: S-EPMC8685610 | biostudies-literature | 2022 Jan

REPOSITORIES: biostudies-literature