Perception of structurally distinct effectors by the integrated WRKY domain of a plant immune receptor.

ABSTRACT: Plants use intracellular nucleotide-binding domain (NBD) and leucine-rich repeat (LRR)-containing immune receptors (NLRs) to detect pathogen-derived effector proteins. The Arabidopsis NLR pair RRS1-R/RPS4 confers disease resistance to different bacterial pathogens by perceiving the structurally distinct effectors AvrRps4 from Pseudomonas syringae pv. pisi and PopP2 from Ralstonia solanacearum via an integrated WRKY domain in RRS1-R. How the WRKY domain of RRS1 (RRS1^WRKY) perceives distinct classes of effector to initiate an immune response is unknown. Here, we report the crystal structure of the in planta processed C-terminal domain of AvrRps4 (AvrRps4^C) in complex with RRS1^WRKY Perception of AvrRps4^C by RRS1^WRKY<

SUBMITTER: Mukhi N 

PROVIDER: S-EPMC8685902 | biostudies-literature | 2021 Dec

REPOSITORIES: biostudies-literature