Cost-utility analysis of antimicrobial stewardship programme at a tertiary teaching hospital in Ethiopia.

ABSTRACT:

Objective

Antimicrobial stewardship (AMS) significantly reduces inappropriate antibiotic use and improves patient outcomes. In low-resource settings, AMS implementation may require concurrent strengthening of clinical microbiology capacity therefore additional investments. We assessed the cost-effectiveness of implementing AMS at Tikur Anbessa Specialised Hospital (TASH), a tertiary care hospital in Ethiopia.

Design

We developed a Markov cohort model to assess the cost-utility of pharmacist-led AMS with concurrent strengthening of laboratory capacity compared with usual care from a 'restricted societal' perspective. We used a lifetime time horizon and discounted health outcomes and cost at 3% annually. Data were extracted from a prospective study of bloodstream infections am

SUBMITTER: Gebretekle GB 

PROVIDER: S-EPMC8685939 | biostudies-literature | 2021 Dec

REPOSITORIES: biostudies-literature