A review of burn symptoms and potential novel neural targets for non-invasive brain stimulation for treatment of burn sequelae.

ABSTRACT: Burn survivors experience myriad associated symptoms such as pain, pruritus, fatigue, impaired motor strength, post-traumatic stress, depression, anxiety, and sleep disturbance. Many of these symptoms are common and remain chronic, despite current standard of care. One potential novel intervention to target these post burn symptoms is transcranial direct current stimulation (tDCS). tDCS is a non-invasive brain stimulation (NIBS) technique that modulates neural excitability of a specific target or neural network. The aim of this work is to review the neural circuits of the aforementioned clinical sequelae associated with burn injuries and to provide a scientific rationale for specific NIBS targets that can potentially treat these conditions. We ran a systematic review, following the PRISMA

SUBMITTER: Thibaut A 

PROVIDER: S-EPMC8685961 | biostudies-literature | 2021 May

REPOSITORIES: biostudies-literature