Association of HSD17B13 rs72613567: TA allelic variant with liver disease: review and meta-analysis.

ABSTRACT:

Background

To assess the association of HSD17B13 rs72613567:TA allelic variant with liver disease, we performed the current review and meta-analysis.

Methods

Seven studies were identified by a search of CNKI,CBM,MEDLINE, PubMed, EMBASE, and CENTRAL databases from inception to November 2021. Odds ratios (ORs) with 95% confidence interval (CI) were calculated using random effects model or fixed effects model based on the between-study heterogeneity. The Stata 14.0 software was employed for data analysis.

Results

Statistical analysis showed that the HSD17B13 rs72613567:TA allelic variant can decrease the risk of hepatocellular carcinoma(HCC) in nonalcoholic fatty liver disease (NAFLD) patients, alcoholic fatty liver disease (ALD) patients and viral hepatitis patients (TA

SUBMITTER: Tang S 

PROVIDER: S-EPMC8686634 | biostudies-literature | 2021 Dec

REPOSITORIES: biostudies-literature