A novel Betaretrovirus discovered in cattle with neurological disease and encephalitis.

ABSTRACT:

Background

The majority of emerging infectious diseases in humans are of animal origin, and many of them are caused by neuropathogenic viruses. Many cases of neurological disease and encephalitis in livestock remain etiologically unresolved, posing a constant threat to animal and human health. Thus, continuous extension of our knowledge of the repertoire of viruses prone to infect the central nervous system (CNS) is vital for pathogen monitoring and the early detection of emerging viruses. Using high-throughput sequencing (HTS) and bioinformatics, we discovered a new retrovirus, bovine retrovirus CH15 (BoRV CH15), in the CNS of a cow with non-suppurative encephalitis. Phylogenetic analysis revealed the affiliation of BoRV CH15 to the genus Betaretrovirus.

Results

BoRV CH15 g

SUBMITTER: Hierweger MM 

PROVIDER: S-EPMC8686636 | biostudies-literature | 2021 Dec

REPOSITORIES: biostudies-literature