Detecting Critical Functional Ingredients Group and Mechanism of Xuebijing Injection in Treating Sepsis.

ABSTRACT: Sepsis is a systemic inflammatory reaction caused by various infectious or noninfectious factors, which can lead to shock, multiple organ dysfunction syndrome, and death. It is one of the common complications and a main cause of death in critically ill patients. At present, the treatments of sepsis are mainly focused on the controlling of inflammatory response and reduction of various organ function damage, including anti-infection, hormones, mechanical ventilation, nutritional support, and traditional Chinese medicine (TCM). Among them, Xuebijing injection (XBJI) is an important derivative of TCM, which is widely used in clinical research. However, the molecular mechanism of XBJI on sepsis is still not clear. The mechanism of treatment of "bacteria, poison and inflammation" and the effect

SUBMITTER: Wu Q 

PROVIDER: S-EPMC8687625 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature