Corneal Structural Changes in Congenital Glaucoma.

ABSTRACT:

Objective

To identify corneal structure differences on quantitative high-frequency ultrasound biomicroscopy (UBM) among subjects with congenital glaucoma compared with controls.

Methods

This prospective case-control study evaluated 180 UBM images from 44 eyes of 30 subjects (18 control and 12 glaucoma, mean age 5.2±8.0 years, range 0.2-25.8 years) enrolled in the Pediatric Anterior Segment Imaging and Innovation Study (PASIIS). ImageJ was used to quantify a comprehensive set of corneal structures according to 21 quantitative parameters. Statistical analysis compared corneal measurements in glaucoma subtypes and age-matched controls with significance testing and mixed effects models.

Results

Significant differences between congenital glaucoma cases and controls were id

SUBMITTER: Drechsler J 

PROVIDER: S-EPMC8688203 | biostudies-literature | 2022 Jan

REPOSITORIES: biostudies-literature