Anatomic Criteria Determine Resectability in Locally Advanced Pancreatic Cancer.

ABSTRACT:

Background

The introduction of multi-agent chemotherapy and radiation therapy has facilitated potential resection with curative intent in selected locally advanced pancreatic cancer (LAPC) patients with excellent outcomes. Nevertheless, there remains a remarkable lack of consensus on the management of LAPC. We sought to describe the outcomes of patients with LAPC and objectively define the multidisciplinary selection process for operative exploration based on anatomical factors.

Methods

Consecutive patients with LAPC were evaluated for pancreatic surgery in the multidisciplinary clinic of a high-volume institution, between 2013 and 2018. Prospective stratification (LAPC-1, LAPC-2, and LAPC-3), based on the involvement of regional anatomical structures, was performed at the t

SUBMITTER: Gemenetzis G 

PROVIDER: S-EPMC8688211 | biostudies-literature | 2022 Jan

REPOSITORIES: biostudies-literature