In utero exposure to near-roadway air pollution and autism spectrum disorder in children.

ABSTRACT:

Importance

Previous studies have reported associations between in utero exposure to regional air pollution and autism spectrum disorders (ASD). In utero exposure to components of near-roadway air pollution (NRAP) has been linked to adverse neurodevelopment in animal models, but few studies have investigated NRAP association with ASD risk.

Objective

To identify ASD risk associated with in utero exposure to NRAP in a large, representative birth cohort.

Design, setting, and participants

This retrospective pregnancy cohort study included 314,391 mother-child pairs of singletons born between 2001 and 2014 at Kaiser Permanente Southern California (KPSC) hospitals. Maternal and child data were extracted from KPSC electronic medical records. Children were followed until: clin

SUBMITTER: Carter SA 

PROVIDER: S-EPMC8688235 | biostudies-literature | 2022 Jan

REPOSITORIES: biostudies-literature