Local Recurrence After Minimally Invasive Curettage For Primary Giant Cell Tumor of Bone With Perioperative Bisphosphonate Is Comparable to Open Curettage: Retrospective Comparison With 9-Year Follow-Up.

ABSTRACT:

Purpose

To compare the long-term oncological outcome of minimally invasive curettage (MIC) with conventional open curettage (OC).

Methods

We studied patients with primary giant cell tumor of bone (GCTB) of extremities who underwent intralesional tumor curettage and cementation and perioperative bisphosphonates from February 2003 to June 2016. All cases were histology-confirmed diagnoses of GCTB. Recurrent GCTB, malignant GCTB, cases in the axial skeleton (pelvis and spine), or cases with bone grafting of the curetted cavity were excluded. The local recurrence-free (LR-free) estimates of the OC and MIC groups were compared. The hazard ratio of a local recurrence was calculated for the various factors of the patients, disease, and treatment.

Results

At a mean follow-up

SUBMITTER: Lau HW 

PROVIDER: S-EPMC8689217 | biostudies-literature | 2021 Dec

REPOSITORIES: biostudies-literature